The mystery of the mysterious diseases

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Migraine, fibromyalgia, are diseases whose origin and cure are unknown. That’s what they say.


Why it hurts so much and so often really is a mystery if what the doctors say is true: that there is nothing abnormal in the time, space and circumstance of pain.


– It shouldn’t hurt you.


It’s the same with pain and other perceptions.


– I’m hungry every day and every hour.


– You shouldn’t be hungry. You are well-nourished. Over-nourished, I would say…


It’s the mystery of why some citizens’ hunger increases when they eat, rather than diminish it.


– I’m more and more hungry. I don’t understand it. No food fixes it…


The brain is a perception manager. It projects hunger, pain, heat, cold, dizziness, fatigue, boredom, euphoria … for reasons that we don’t always understand. If we have been several days without food it’s understandable that the brain reminds us, with hunger, that the body needs energy, but it doesn’t make sense for the brain to project the urge to eat on us if we are a little overweight.


The disease of chronic, unwarranted hunger is a mystery. The researchers track the chemistry of hunger in search of molecules that turn the need into a compulsive addiction. They always find one and make the media bells sound.


Those molecules are also found in that kind of pain.


The researchers are optimistic.


– In recent years there has been considerable progress in the understanding of pain. In the future we’ll have new drugs. Controlling the suffering won’t be a problem.


The problem of the future is that it’s never present in this issue.


The issue of hunger is not improving. Every day thousands of people die because of chronic insatiable hunger. The problem may even be getting worse.


The pain also wreaks havoc. Every day thousands of citizens die by chronic, insatiable consumption of analgesics. The problem may even go from bad to worse.


Reasonable, economic management of perceptual resources is not guaranteed. The brain doesn’t have a smart natural condition. Rather the opposite. It’s the individual’s job to channel the brain’s biological dynamics, selected for harsh and competitive environments, and adapt them to the universe of “everything is a hundred yards tall” and be safe.


There are children hunger and chronic pain, insatiable.


Some believe that everything is because of the inconsistency between what the alarmist genetics claims and what the culture of abundance offers. The human molecules of pain and hunger are the same as those of flies and worms in the laboratory. We should to track the differences between cultures.

– Culture, you say? Children have no culture, but they have migraine and fibromyalgia. It’s the genes and the undisclosed mysterious thing. There are entire families affected by this.

Curious and erroneous idea of culture. It seems that there can’t be cultural impregnation until we access the “use of reason”.


The sapiens brain (ma non troppo) is, by what genetics dictate, candid, imitating and “schoolable”. It absorbs culture since the first hours of life.


Parents, teachers and friends are always around the child projecting words and examples, said and dones. The child’s brain is a pasive schoolchild that takes everything that happens and hears in order to process it according to rules we don’t know about.


This week a patient came to my office with migraine, neck pain, rather chubby, moderately discouraged and she was a smoker. She did a good job of schooling in “my brain and it’s “I”” … She no longer has migraines, her neck doesn’t hurt (there was also a great pedagogical work of two excellent “neurophysic therapists”) she has earned a few anti-kilos, she is courageous after quitting the antidepressants she no longer absurdly inhales addictive toxic smoke..


She is an ideal patient, intelligent and hardworking.

For her there is no more mystery. It’s all simple.

>Evaluative disfunction as a risk factor

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A reasonably healthy body managed by a mistaken, alarmist brain that maintains defensive programs needlessly is an abused body, subjected to physical burdens that undermine its integrity. Defense programs are justified when there is a noxious state or agent.

The program of preventive removal of the ingested (ie nausea to cause vomit) is biologically justified when we have eaten something dangerous, or when an animal stuffs itself with food and then regurgitates it to feed the brood or to hide food in a safe place. Activating vomit during a migraine attack or vertigo only produces discomfort, suffering and loss of energy (food). The body tends to activate preventively the nausea when it assesses internal problems. Germs and toxic substances go in through the digestive tract. If something goes wrong internally, the noxious agent might still be in the stomach, so the stomach-pumping program is turned on. Facial pain, toothache or muscle-skeletal system pain are not accompanied by nausea. The theoretically noxious is still at the entrance (mouth) or is a matter of mechanical stress (muscle-skeletal system). Biologically, vomiting does not make sense.

Keeping the hunger program on and eagerly promoting it despite overweight generates all kinds of physical inconvenience. Hunger is for when there isn’t any food available but can be found if one tries hard enough. It makes no sense if you have any extra kilos or if there is no chance of finding a tiny bite.

Managing the organism healthily involves being right in the decision to turn on and off and maintain programs, obtaining profit from it.

The erroneous assessment of relevant structural damage in the spine (“I have arthritis, pinches, hernias…”) involves the turning on of defensive programs that cancel the articular function, contracture of inadequate muscles and increase of mechanical stress with each action. A spine with “wear” needs free joints, little mechanical load, freedom and promotion of movement, trust … not fear of movement.

The erroneous assessment of disease activates the “sickness response” that promotes the  behavior of feeling “coming down with the flu” (sore, tired, unmotivated) not being sick. In the case of fibromyalgia, the brain maintains discouragement active (fatigue) and punishment (pain) of movement “as if” there was disease. Actually, the disease is generated by an erroneous evaluation of disease, the stubbornness in defending the idea that fibromyalgia is a disease (in the classical way) when the pathogenic state is the mismanagement of a healthy brain “as if” the individual was sick.

The stress program does its job: alerting the individual from an uncoded new incidence, measuring it, evaluating it, giving it relevance, selecting the coping resources and proceeding to activate the most appropriate behavior. After the event, shutting down the program. Stressing out is not working too hard, but doing it with a continuous assessment of shock, threat, catastrophism, subjection to an unknown hierarchy… being helpless…  

The program of feeling depressed makes sense when the reality at that moment is averse and doesn’t offer a solution until either circumstances have changed or a recent negative event has been sufficiently ruminated and digested. Continuous assessment of helplessness, low self-esteem or other’s, in the objective absence of weakness or adversity of the surroundings, cancels the motivational resources and condemns the individual to inaction.

The catastrophist assessment makes sense when there has been a negative factor and must be analyzed to learn how to avoid it or deal with it properly in the future. Once the analysis is done, the reflective period is turned off and the individual gets his or her act together to work towards his or her goals.

– Your brain doesn’t manage the programs properly. It evaluates the organism’s state wrongly. It sees danger, failure, vulnerability, illness, frailty. That’s why you have symptoms… that is, programs … They are on and should be off.

– I disagree. I’m sick.

– If you think so, you’re feeding your brain’s erroneous evaluations, which is bad.

– I was told that my brain has lost volume in the cortex. That doesn’t seem normal to me.

– The connections between neurons are cheered up with action and turned off with discouragement. Your brain’s cortex has thinned because it has no stimuli. They are discouraged. Pleasure is requisitioned.

Confusing the appearance of disease with actual disease is not harmless. Not considering the brain’s evaluative error as a pathology that must be fought with the restoration of the health belief is a mistake. Defending and claiming the disease condition of a healthy organism is not harmless.

“… migraine, fibromyalgia … are mysterious illnesses without treatment …”

When will there be a serious, rigorous consideration of that omnipresent and overflowing category of diseases of cultural mediation?

It doesn’t look good…

>The brain doesn’t hurt

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Once again, Descartes

Neurologists like to say that “the brain does not hurt”. When the individual is awake, we importune him or her with all sorts of disturbing stimuli:

– Does it hurt?

– No

The brain has no “pain receptors”. That explains why it doesn’t hurt. Any pain generated in the head necessarily has to come from the meninges and large blood vessels that do have the required receptors that detect the pain released by the tissues, when these are appropriately disturbed.

Generalizing this conclusion to other perceptions, we could also state that the brain does not smell, see, hear, taste, touch or feel heat or cold. The brain may be sad or happy, relaxed or anxious. We can stimulate specific places with electrodes.

– What do you feel?

– Deep sadness.

Tissues express their adversity through pain, but brain cells, depending on how the serotonin, dopamine, endorphins, adrenaline and other molecules go, do so setting moods and emotions free, that are detected by the corresponding receptors transforming them into signals that reach consciousness, where they are felt by the individual.

Does it hurt? Something is wrong about the tissues.

Are you feeling sad? Something is wrong about the neurons of sadness.

The statement that the brain does not hurt comes in handy for everyone. Everyone wants the brain to be limited to receiving Cartesian signals of pain and amplifying or ignoring them, whichever is more appropriate. We can manipulate those signals promoting the comfort of the tissues with diets, postures, exercises and adequate rests while we avoid the cerebral mood amplification modifying our personality and facing those that are inadequate.

We can manipulate pain signals with drugs that reduce and block them.    

When it comes to sadness and other neural disorders we can go deeper into the matter. We increase serotonin, opiates and cannabinoids, reduce the tone of dopamine and adrenaline and the brain will stop secreting discouragement, hearing voices and distress.

I like asking leading questions to the residents.

– How many eyes do we have?

– Two

– Well, there are two eye cameras that go around the world gathering data, but really there is only one eye, the eye of the mind. It’s in the brain. It is the one that really sees, or rather, builds what we see. It’s also the one that “takes looks”.

Eyes have no vision receptors, but receivers of electromagnetic radiation (light). In the retina, there are light and no-light receptors (darkness). Both are essential for the brain to see edges, contrasts, elementary and complex forms… The eyes do not see faces or trees. It is the brain that integrates visual memory (intelligence) and data from the retina and projects the result on our conscience, right when it crosses this mysterious area of perception.

It’s not nociceptors (receptors of nuisance) that build pain. They simply take data of consummate or imminent threat in the tissues. With these data and those provided by the memory of pain (nociceptive intelligence) the brain hurts … projects pain at a time and place for a reason and for something…

The something-gen function, the one that causes pain, lives in the brain, like the “vision-gen”, “smell-gen” and “sound-gen”.

– Doctor, you’re repeating the same thing over and over again…

– I know, but the error of Descartes is well caught in the minds of the pain sufferers and their caregivers while the successes of the great René, his rationalism, the experimental method, the methodical doubt, distrust in what authorities say and senses … are not part of our thinking and attitudes.

The brain may not hurt but it causes pain. The one that surely suffers from pain is the individual.

– It’s not your column that hurts. It is the brain.

– So it’s ME …

– Not exactly. It’s your brain …

– Yeah, ME … The brain is ME!

– No. YOU are your brain and YOU. Both are important.

– They call it dualism …

– Naturally, but there are many ways to understand … A single cell is dualistic. Things happen inside of it (the intracellular) and the result of all this produces information that comes out (extracellular) and so the cell knows something about itself. There is an inside and an outside but they are integrated, interrelated. The brain would be the equivalent in body of what is inside the cells. The individual would be the outside …

– Just leave it … all I know is that it hurts

– All I know is that this indicates that your brain has decided to hurt … here and now …

>Process to information

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The metaphor of the brain as an information processor, in this computer era we live in, is inevitable.

– The brain is like a computer. It processes information.

There are sufferings (migraine, fibromyalgia) characterized by chronic or repetitive pain in which no alterations that explain properly the symptoms are found. The sufferer is given diagnostic labels, obscure hypotheses about its origin and insufficient relief remedies.

Experts have just found molecular alterations that suggest that something wrong happens in the neural network and use the metaphor.

The brain processes information wrong. Turns banal stimuli into painful. Everything becomes pain.

If someone is interested in the information itself, in its quality, the experts say …

– There is not much information. We should organize sensitization campaigns, explain clearly the obscurities of the problem.

– I inform you: migraine, fibromyalgia… are diseases with a mysterious origin, they have no cure …

The sufferers feel relieved when they’re given a label, to later plunge into despair when they realize that the information condemns them to live in a body governed by a pathological brain, sick, making daily life a living hell.

– Your brain processes information wrong. It’s hyper-excitable, sensitive. Genes, emotions, stress… have made it that way.

The sufferers don’t ask about information. Neither do experts, of course. They are “the parents of the child”.

Perhaps some rambling mind could be skeptical about this.

– Couldn’t it be that the problem is in the information? I don’t know… Sorry, don’t misunderstand me… but couldn’t it be that the information is not… let’s say… good?

– Our information is scientific. From science, we know that we know nothing but we are identifying molecules that don’t measure up.

– It occurs to me that, well… thinking about computers… that brains have… viruses. A brain is like a computer, connected to a network in which information flows freely.

– Well… that happens in movies. In the real brain there are only molecules: serotonin, dopamine, norepinephrine, endorphins, endocannabinoids, glutamate, genes… of course, there are no chips or circuits. We are not robots.

– Should I confide then in your information as an expert?

– It is the best possible one.

Is the brain really the responsible one? Does it process badly the best possible information? Or maybe, this is just an idea… could it be that it processes excellently the worst possible information?

– Are you suggesting that we are the experts the problem? That we should be processed?

– It was just a hypothesis …

>Everyone has migraines!

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Yesterday was the World Day Against Migraine.

Migraine is doing well. Experts say that it has risen two points of incidence in the population.

We have promising developments but there is a lack of information, marketing.

– We need to educate, sensitize the population.

Obviously the most sensitive on the topic of migraine are neurologists. Migraine is a syndrome of central sensitization. There are investigations that confirm it. The most sensitive, the neurologists, suffer migraine almost ten times more than the “normal” population (under-sensitized).

It makes sense. If we properly sensitize the under-sensitized population (normal) we manage to bring the incidence of the neurologists closer to theirs. It is ambitious, but not impossible: over 50% of the population has migraines. A real challenge.

In the development on information about genes related to various enzymes that don’t metabolize bad molecules well (histamine, glutamate …) there are some novelties. Migraine, experts still argue, is there since we are born.

Once acquired that migraine is congenital, the only thing we have left is to follow the thousands of canons of things we have to avoid, the terrible triggers of migraine. We must avoid aged cheese, chocolate, weather changes and hormonal stresses, electromagnetic radiation, alcohol shots,…

What should we do? Of course, ask an expert.

Which one? You pick it yourself. We have lots of kinds. If you don’t like the first one, don’t worry. We have some others too. The one that works will be the right one.

Things do not always go well… for the sufferer. Migraine strengthens. It becomes more frequent, intense and rebellious to its proposals.

Experts say that there is not much left to do with this troop. They are not consulted enough and take painkillers the way they want. They are drug addicts in power (the genes again) and don’t know how to deal with the pain without the sedative.

– You have to take the painkiller at the first sign of pain. Don’t wait.

– I do, but it doesn’t work anymore.

– You have taken too many painkillers. You’ve self-medicated.

– You prescribed it.

– Yes, but I warned you not to have too many.

Sufferer unions demand to be considered ill.

The Patronal agrees:

– Migraine is a chronic brain disease.

You already know the purpose of this hidden blog:

– Migraine emerges from a healthy body by mismanagement of a mistaken brain.

The person with migraine isn’t born like that. It becomes like that. That person learns, imitates.  

Migraine is a syndrome of conversion. There are beliefs underneath.

The solution is the reconversion, the disbelief of the believed. Desensitization. Tolerance to triggers. Good life. Carelessness.

– Now I drink wine and eat chocolate and they no longer give me migraines. Credible!

I already warned you:

From what we believe, we create